Mike Bollong

Company: The Scripps Research Institute

Job title: Early Career Endowed Roon Chair for Cardiovascular Research, Assistant Professor

Seminars:

Unearthing Novel Pharmacology Targeting the Hippo Pathway for Regenerative Organ Repair 9:00 am

Championing novel small molecules and associated cellular mechanisms of action for contextually inactivating Hippo signaling Categorizing strategies to overcome off organ hyperplasia Pinpointing proof of concept efficacy data in rodents and pigs demonstrating regenerative repairRead more

day: Conference Day Two

Panel Discussion: Harnessing YAP/TAZ as an Alternative to Modulating TEAD: What More Needs to be Done? 10:00 am

What are the key events leading to YAP/TAZ activation Should we activate YAP/TEAD by directly binding it or through inhibiting upstream targets including the hippo signaling pathway ? What’s the merit of either approach? What are the current limitations of these molecules and potential ways to improve them? What are the potential liabilities/concerns with modulating…Read more

day: Conference Day Two