Adeela Kamal

Company: SpringWorks Therapeutics

Job title: Senior Vice President, Head of Discovery Biology & Translational Medicine

Seminars:

Biomarker-Guided Drug Development of YAP/TAZ-TEAD inhibitors 12:15 pm

SW-682: preclinical data for a novel TEAD inhibitor for Hippo-mutant cancers Overview of potential biomarkers for patient stratification, target engagement and molecular response Biomarkers for YAP activation as oncogenic driver or resistance mechanism to targeted therapiesRead more

day: Conference Day One

Roundtable Discussion: Exploring What More Needs to be Done to Develop & Establish Hippo Pathway Biomarkers 12:45 pm

How do we find evidence for target/pathway regulation biomarkers? Does inhibiting TEAD create a measurable functional effect on disease that could act as a biomarker? Are we selecting the right patients with the right TEAD isoform mutations? Are there biomarkers of resistance and how do we find them? What is the feasibility for clinical biomarker…Read more

day: Conference Day One